The wellness world sells complexity. We do the opposite — cutting the supplement noise down to the few interventions with real human evidence — from healthspan and biological age to GLP-1 and senolytics — with clean ingredients and simple protocols you'll actually keep.
Read: the short list →No 30-pill stacks. From healthspan and biological age to GLP-1, senolytics and mitophagy, we focus on the short list of things that actually move the needle — and tell you honestly what doesn't.
GLP-1 drugs, rapamycin, taurine, urolithin A, senolytics, epigenetic age clocks and NMN — the year's biggest longevity buzzwords, sorted into real evidence vs. noise. Read the 2026 briefing →
Free Tool · InteractiveYour birthday tells your chronological age — your habits tell a different story. Estimate your biological age in 60 seconds. Free, science-based, no sign-up. Try it →
mTOR · NewIt makes mice live longer and biohackers swear by it. But does rapamycin slow aging in humans? The clean read on the PEARL trial & the hype. Read →
GLP-1 · NewA 2026 trial says semaglutide slowed biological aging on epigenetic clocks. Real breakthrough or hype? The clean read on GLP-1 & longevity. Read →
Cellular Energy · NewA Krebs-cycle molecule is 2026’s loudest “8 years younger” supplement. Striking mouse data, thin human proof — the clean read on AKG. Read →
Glycation · NewSugar slowly caramelizes your collagen — and in 2026 an enzyme reversed the “permanent” damage in a dish. The clean read on AGEs. Read →
Antioxidants · NewA mushroom compound your body can't make but built a special door to keep. Strong human associations, one small trial — the clean read. Read →
Autophagy · NewThe autophagy-triggering molecule in cheese and cereal is 2026’s quiet longevity pick. Strong epidemiology, thin proof — the clean read. Read →
NAD+ · NewThe most hyped molecule in the anti-aging aisle definitely raises NAD+ — but does it slow aging? The clean, evidence-based read. Read →
Senescence · NewThey promise to flush the “zombie cells” that age you. Stunning in mice, still tiny trials in humans — the clean read. Read →
Amino Acids · NewA 270,000-person study tied higher tyrosine to a shorter lifespan in men — not women. Does your brain supplement matter? Read →
Fatty Acids · NewA humble fat from milk and cheese is sold as the first essential fatty acid in 90 years. Does the science hold up? Read →
Mitochondria · NewThe mitophagy supplement from pomegranates has real human trials behind it — muscle, immunity and the hype, read cleanly. Read →
Amino Acids · New2023’s longevity superstar took two big hits in 2025. What the taurine evidence really shows now. Read →
Supplements · NewThe handful of compounds with real human evidence — and the long list of popular ones that don't deserve your money. Read our latest →
Labels · BioavailabilityThird-party testing, COAs, proprietary blends and bioavailable forms — how to tell a clean product from clever marketing. Read →
Food FirstMost of longevity is built on a plate, not in a bottle. The dietary patterns the evidence keeps pointing to. Read →
Basics · HealthspanSleep, VO2 max, strength, sunlight — the unglamorous fundamentals that outperform almost any supplement. Read →
MythsWe pressure-test viral claims — NMN, resveratrol, “detox” — so you don't waste years or savings. Read →
ProtocolsClean, minimal routines you can actually keep — built from evidence, not an influencer's affiliate links. Read →
"Clean" isn't a marketing word here. It means clean evidence, clean ingredients, and a clean conscience — we'd rather tell you to save your money than sell you another bottle you don't need.
